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Structure of 99465-10-8
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7-Bromoquinolin-2(1H)-one features a bromine substituent at the C7 position of a quinolin-2(1H)-one scaffold, imparting enhanced electrophilicity and facilitating downstream functionalization via cross-coupling reactions. This bench-stable heterocycle serves as a key intermediate in the synthesis of bioactive molecules and advanced materials.
7-Bromoquinolin-2(1H)-one serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C7 position via cross-coupling reactions. Its quinolinone core provides a rigid, planar scaffold with favorable solubility and stability for downstream derivatization. The bromo group facilitates palladium-catalyzed transformations, while the lactam functionality offers hydrogen-bonding capacity and enhanced metabolic stability—making it a practical intermediate for targeted synthesis of kinase inhibitors and other bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: