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Structure of 99980-40-2
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This pyridinylpropanamine derivative features a sterically hindered tertiary amine linked to a pyridine ring, enabling efficient coordination in catalytic systems. The para-positioned nitrogen delivers strong electron-donating character, enhancing reactivity in transition metal complexes. Its bench-stable nature supports reliable use in synthetic workflows requiring robust ligand performance.
2-(Pyridin-3-yl)propan-2-amine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocyclic scaffolds. Its tertiary amine functionality offers favorable solubility and basicity, while the pyridyl group provides a robust handle for metal-catalyzed coupling reactions. The sterically hindered neopentyl-like structure enhances metabolic stability and facilitates purification. This compound functions effectively in Suzuki-Miyaura, Buchwald-Hartwig, and reductive amination protocols, supporting efficient synthesis of targeted pharmaceutical intermediates.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: