2'-O-Me-modified Nucleosides
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2'-O-Me modified nucleosides refer to modifications in which the oxygen atom at the 2' position in the sugar structure of the nucleoside is replaced by a methyl group (-CH3). Specifically, 2'-O-methylation refers to the addition of a methyl group (-CH3) to the 2' position of RNA or nucleotides, thereby changing the chemical and biological properties of the nucleoside. 2'-O-methyl modified nucleosides are widely used in RNA chemistry and molecular biology research and have a variety of potential functions and applications.
2'-O-Me-modified Nucleosides
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