2',3'-O-Isopropylideneuridine

Name: 2',3'-O-Isopropylideneuridine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 362-43-6
Cat. No. CS-W010029
Purity≥98%
MDL No.MFCD00034509

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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2',3'-O-Isopropylideneuridine|CS-W010029

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General Information

CAS No. 362-43-6
Cat. No. CS-W010029
Purity ≥98%
MDL No. MFCD00034509
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₂H₁₆N₂O₆
Molecular Weight 284.27
Synonym(s) 2',3'-O-Isopropylidene-D-uridine
SMILES OC[C@@H]1[C@@H](OC(C)(C)O2)[C@@H]2[C@H](N3C(NC(C=C3)=O)=O)O1

Description

Visit our Sensor Applications portal to learn more.Selected application examples

Application

2',3'-O-Isopropylideneuridine serves as a key protected nucleoside intermediate in the synthesis of antiviral agents and oligonucleotide building blocks. The isopropylidene acetal stabilizes the 2',3'-diol moiety under acidic conditions, enabling selective functionalization at other hydroxyl sites. Its bench-stable nature and compatibility with standard glycosylation and phosphorylation protocols make it a practical choice for iterative synthetic sequences in medicinal chemistry and nucleic acid research.

Synthesis

Route1
- 191479-26-2
- ~98%
- In-stock
  
  362-43-6
References
- Tetrahedron Letters, , vol. 53, # 29 p. 3758 - 3762
Route2
- 67-64-1
- 58-96-8
- ~99%
- In-stock
  
  362-43-6
References
- Journal of Medicinal Chemistry, , vol. 50, # 5 p. 915 - 921
Route3
- 102147-76-2
- ~99%
- In-stock
  
  362-43-6
References
- Tetrahedron Letters, , vol. 33, # 9 p. 1177 - 1180

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 102.78
LogP -1.0536
H_Acceptors 7
H_Donors 2
Rotatable_Bonds 2

Other Classifications

Bioactive Molecules Dye and Bio-assay Reagents

Life Science Nucleosides & Nucleotides 2'-O-Me-modified Nucleosides

Chemical Biology Nucleic Acid Chemistry Methylated Nucleosides

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleobases and their Analogs

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleoside Analogs

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleosides

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2',3'-O-Isopropylideneuridine

CAS No. 362-43-6

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