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CS-W001157 4
Total: USD 88.00

iST2-1

  • CAS No. 1019158-02-1

  • Cat. No. CS-0052271
  • Molecule weight378.42
  • Purity≥96%
  • MDL No.MFCD14826567

*For research and further manufacturing use only, not for direct human use.

iST2-1|CS-0052271

Structure of 1019158-02-1

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General Information

  • CAS No. 1019158-02-1
  • Cat. No. CS-0052271
  • Purity ≥96%
  • MDL No. MFCD14826567
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₂₂N₂O₄
  • Molecular Weight 378.42
  • Synonym(s) None
  • SMILES COC1=CC=C(C=C1)C1CCCN1CC1=CC=C(O1)C1=CC=CC=C1[N+]([O-])=O

Description

iST2-1 is a bench-stable, moisture-tolerant boronate ester featuring a sterically hindered aryl group that enables efficient cross-coupling under mild conditions. This reagent integrates seamlessly into Suzuki-Miyaura protocols, delivering high yields with minimal purification burden.

Application

iST2-1 serves as a robust building block for the synthesis of complex heterocyclic scaffolds, enabling efficient construction of pharmaceutically relevant core structures. Its well-defined reactivity profile supports reliable coupling and cyclization reactions under standard conditions, with demonstrated compatibility across diverse functional groups. Bench-stable and readily purified, it facilitates scalable synthesis workflows in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   68.75
  • LogP   5.2005
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   6

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