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Structure of 109-12-6
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COMU is a novel reagent which mediates coupling reactions with efficiencies comparable to HATU [1,2].It has higher solubility than HATU and HBTU. Furthermore, it is not explosive under normal operating conditions and is less likely to exhibit allergenicity compared to other coupling reagents. Recently, the application of COMU in the preparation of esters has been demonstrated [3]. Associated Protocols and Technical ArticlesGuide to Selection of Coupling ReagentsLiterature references[1] A. El-Faham, et al. (2009) Chem. Eur. J., 15, 9404. [2] A. El-Faham & F. Albericio (2010) J. Pept. Sci., 16, 6. [3] Jean-dAmour, et al. (2011) Org. Lett., 13, 2988.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: