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Structure of 1683-85-8
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5-Fluoropyrimidin-2-amine serves as a key heterocyclic scaffold in medicinal chemistry, integrating a fluorine atom at the C5 position with an amino group at C2. This combination imparts enhanced metabolic stability and targeted electronic properties, enabling efficient incorporation into kinase inhibitors and antiviral agents. The molecule exhibits robust bench stability and compatibility with standard synthetic protocols.
5-Fluoropyrimidin-2-amine serves as a key building block in medicinal chemistry, enabling the synthesis of fluorinated heterocyclic scaffolds prevalent in kinase inhibitors and antiviral agents. Its reactivity facilitates nucleophilic substitution at C5 and amine-directed functionalization, supporting diverse coupling strategies. The compound exhibits good bench stability and compatibility with standard purification techniques, making it a practical choice for iterative library synthesis and API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: