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Structure of 1190865-44-1
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This trifluoromethyl ketone features a 3,5-dichloro-4-fluorophenyl moiety linked to a trifluoromethyl group via a carbonyl. The electron-deficient aryl ring enhances reactivity in nucleophilic substitution and coupling processes. Bench-stable and moisture-tolerant, it serves as a key intermediate in the synthesis of fluorinated pharmaceuticals and agrochemicals.
1-(3,5-Dichloro-4-fluorophenyl)-2,2,2-trifluoroethan-1-one serves as a key electrophilic building block in medicinal chemistry, enabling efficient construction of fluorinated aryl ketones via standard nucleophilic addition reactions. Its trifluoromethyl ketone functionality exhibits enhanced metabolic stability and modulates lipophilicity, facilitating integration into bioactive scaffolds. The molecule demonstrates robust bench stability and compatibility with common purification methods, supporting scalable synthesis workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: