(R)-1-(2-Methoxypyridin-4-yl)ethanamine

CAS No. 1213559-80-8
Cat. No. CS-0196581
Purity≥97%
MDL No.None

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(R)-1-(2-Methoxypyridin-4-yl)ethanamine|CS-0196581

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General Information

CAS No. 1213559-80-8
Cat. No. CS-0196581
Purity ≥97%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₂N₂O
Molecular Weight 152.19
Synonym(s) None
SMILES C[C@H](C1=CC(=NC=C1)OC)N

Description

(R)-1-(2-Methoxypyridin-4-yl)ethanamine features a chiral ethanamine side chain attached to a methoxypyridine heterocycle, delivering a rigid, electron-rich scaffold ideal for asymmetric synthesis. The para-methoxy group enhances solubility and modulates electronic properties, while the (R)-configuration ensures high enantioselectivity in catalytic applications. This bench-stable, moisture-tolerant building block integrates seamlessly into pharmaceutical intermediates and ligand design.

Application

(R)-1-(2-Methoxypyridin-4-yl)ethanamine serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of pyridine-containing bioactive molecules. Its stability under standard reaction conditions and compatibility with common functional groups facilitate efficient coupling and derivatization. The molecule functions effectively in transition-metal-catalyzed transformations and provides access to pharmacologically relevant scaffolds through straightforward amine manipulation.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 48.14
LogP 1.1099
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 2

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-1-(2-Methoxypyridin-4-yl)ethanamine

CAS No. 1213559-80-8

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