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Structure of 1273564-99-0
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3,3-Difluorocyclobutanone features a strained cyclobutanone ring bearing two fluorine atoms at the C3 position, conferring enhanced electrophilicity and metabolic stability. This difluorinated scaffold serves as a valuable building block in medicinal chemistry, enabling incorporation into bioactive molecules where lipophilicity and resistance to oxidative degradation are critical.
3,3-Difluorocyclobutanone serves as a valuable building block in medicinal chemistry, enabling the construction of fluorinated heterocyclic scaffolds through established cycloaddition and nucleophilic addition reactions. Its strained ring system enhances reactivity while maintaining bench stability, facilitating efficient functionalization under mild conditions. The geminal difluoro substitution imparts metabolic stability and modulates electronic properties, making it particularly useful in optimizing pharmacokinetic profiles.
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GHS Pictogram :
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GHS No : GHS02
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Signal Word : Warning
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H226
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501
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Lot numbers can be found on the outside label of a product: