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Structure of 133921-27-4
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4-Iodo-3-methylphenol features a sterically accessible phenolic hydroxyl group flanked by an iodine substituent and a methyl group, enabling direct functionalization in cross-coupling reactions. This bench-stable compound integrates readily into complex molecular architectures under standard conditions.
4-Iodo-3-methylphenol serves as a versatile building block in cross-coupling reactions, enabling efficient construction of biaryl scaffolds under palladium catalysis. The iodide functionality provides high reactivity in Suzuki, Stille, and Negishi couplings, while the phenolic hydroxyl and methyl group offer orthogonal handles for further derivatization. Bench-stable and readily purified by recrystallization, it functions reliably in medicinal chemistry and materials synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: