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CS-W001157 4
Total: USD 88.00

(3S,4R)-3-Fluoro-1-methylpiperidin-4-amine

  • CAS No. 1350629-55-8

  • Cat. No. CS-0884520
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(3S,4R)-3-Fluoro-1-methylpiperidin-4-amine|CS-0884520

Structure of 1350629-55-8

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General Information

  • CAS No. 1350629-55-8
  • Cat. No. CS-0884520
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃FN₂
  • Molecular Weight 132.18
  • Synonym(s) None
  • SMILES CN1C[C@@H]([C@@H](CC1)N)F

Description

This chiral piperidine amine features a fluorinated stereocenter and a methylated nitrogen, enhancing metabolic stability and membrane permeability. The (3S,4R) configuration ensures optimal binding affinity in target-directed applications. Designed for synthetic efficiency, it integrates readily into bioactive scaffolds under standard conditions.

Application

(3S,4R)-3-Fluoro-1-methylpiperidin-4-amine serves as a versatile chiral building block in medicinal chemistry, enabling the construction of fluorinated piperidine scaffolds prevalent in bioactive molecules. Its defined stereochemistry and functional group pattern facilitate predictable reactivity in amide coupling, alkylation, and cyclization processes. The compound exhibits good bench stability and compatibility with standard purification methods, supporting efficient integration into multi-step synthetic sequences for drug discovery applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   29.26
  • LogP   -0.0127
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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