Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Fluoro-2-methyl-6-nitroaniline

  • CAS No. 147285-87-8

  • Cat. No. CS-0037939
  • Molecule weight170.14
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Fluoro-2-methyl-6-nitroaniline|CS-0037939

Structure of 147285-87-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 147285-87-8
  • Cat. No. CS-0037939
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇FN₂O₂
  • Molecular Weight 170.14
  • Synonym(s) 4-fluoro-2-nitro-6-methylaniline
  • SMILES CC1=C(C(=CC(=C1)F)[N+](=O)[O-])N

Description

4-Fluoro-2-methyl-6-nitroaniline features a trifunctional aromatic core with electron-withdrawing nitro and fluorine groups paired with an activating methyl substituent. This combination enables selective coupling reactions under mild conditions, making it valuable for synthesizing functionalized heterocycles and pharmaceutical intermediates in biopharmaceutical development workflows.

Application

4-Fluoro-2-methyl-6-nitroaniline serves as a versatile building block in medicinal chemistry, enabling direct incorporation into heterocyclic scaffolds via nucleophilic aromatic substitution or subsequent reduction of the nitro group. The fluorine and methyl substituents provide orthogonal reactivity and steric modulation, while the nitro group facilitates downstream functionalization. Bench-stable and amenable to standard purification methods, it functions reliably in multi-step syntheses requiring precise regiocontrol.

Synthesis

  • Route1

    References

    • WO2013/148603 A1, ;
  • Route2

    References

    • WO2013/148603 A1, ;
  • Route3

    References

    • Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 2 p. 257 - 262

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   69.16
  • LogP   1.62452
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-Fluoro-2-methyl-6-nitroaniline sigma4-Fluoro-2-methyl-6-nitroaniline manufacturer4-Fluoro-2-methyl-6-nitroaniline price4-Fluoro-2-methyl-6-nitroaniline structure4-Fluoro-2-methyl-6-nitroaniline SDSbuy 4-Fluoro-2-methyl-6-nitroaniline4-Fluoro-2-methyl-6-nitroaniline supplier4-Fluoro-2-methyl-6-nitroaniline uses4-Fluoro-2-methyl-6-nitroaniline molecular weightprice of 4-Fluoro-2-methyl-6-nitroaniline4-Fluoro-2-methyl-6-nitroaniline chemical name formula of 4-Fluoro-2-methyl-6-nitroaniline
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label