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Structure of 1537892-36-6
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Mal-PEG3-NHS ester is a bifunctional crosslinker featuring a maleimide group conjugated to a PEG spacer and an NHS ester terminus. This compound enables site-specific bioconjugation via thiol-Michael addition at the maleimide end, while the NHS ester facilitates amine coupling under physiological conditions. The PEG3 spacer provides enhanced solubility and reduced steric hindrance, improving reaction efficiency in protein labeling and antibody-drug conjugate synthesis.
Mal-PEG3-NHS ester serves as a versatile bifunctional crosslinker, enabling efficient conjugation of biomolecules via amine-reactive NHS ester and maleimide-thiol ligation. The PEG3 spacer provides enhanced solubility and reduced steric hindrance, facilitating reliable labeling in aqueous environments. Its stability under physiological conditions and high selectivity for thiol groups make it ideal for site-specific bioconjugation workflows in antibody-drug conjugate development and protein modification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P405-P501
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Lot numbers can be found on the outside label of a product: