(4-Chloropyridin-2-yl)methanamine

CAS No. 180748-30-5
Cat. No. CS-W004866
Purity≥97%
MDL No.MFCD07374904

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(4-Chloropyridin-2-yl)methanamine|CS-W004866

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Description

(4-Chloropyridin-2-yl)methanamine features a pyridine ring bearing a chloro group at the 4-position and a primary amine tethered to the 2-position, delivering a robust, electron-deficient heterocyclic scaffold. This compound integrates readily into medicinal chemistry campaigns, offering a handle for conjugation and structural diversification in target-directed synthesis.

Application

(4-Chloropyridin-2-yl)methanamine serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the pyridine ring and side-chain amine for downstream derivatization. Its bench-stable nature and compatibility with standard coupling reactions facilitate efficient access to heterocyclic scaffolds, including kinase inhibitors and bioactive nitrogen-containing frameworks.

General Information

CAS No. 180748-30-5
Cat. No. CS-W004866
Purity ≥97%
MDL No. MFCD07374904
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₇ClN₂
Molecular Weight 142.59
Synonym(s) C-(4-CHLORO-PYRIDIN-2-YL)-METHYLAMINE
SMILES ClC1=CC(=NC=C1)CN

Computational Chemistry Data

TPSA 38.91
LogP 1.1937
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05
Signal Word : Danger	UN#: 3265
Class : 8	Packing Group : Ⅱ
Hazard Statements : H314-H318
Precautionary Statements : P260-P264-P280-P304+P340-P330-P331-P363-P405-P501

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Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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(4-Chloropyridin-2-yl)methanamine

CAS No. 180748-30-5

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