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CS-W001157 4
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(E)-Methyl 4-aminobut-2-enoate hydrochloride

  • CAS No. 213125-87-2

  • Cat. No. CS-0187948
  • Molecule weight151.59
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(E)-Methyl 4-aminobut-2-enoate hydrochloride|CS-0187948

Structure of 213125-87-2

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General Information

  • CAS No. 213125-87-2
  • Cat. No. CS-0187948
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₀ClNO₂
  • Molecular Weight 151.59
  • Synonym(s) None
  • SMILES O=C(/C=C/CN)OC.Cl

Description

(E)-Methyl 4-aminobut-2-enoate hydrochloride features a conjugated enoate system paired with a primary amine, enabling efficient coupling in synthetic transformations. This bench-stable salt form enhances solubility and handling in aqueous or polar organic media, facilitating use in peptide coupling, heterocycle synthesis, and bioconjugation workflows.

Application

(E)-Methyl 4-aminobut-2-enoate hydrochloride serves as a versatile building block for heterocyclic synthesis, enabling efficient access to pyrrolidine and piperidine derivatives via cyclization reactions. The conjugated enamine system facilitates Michael additions and palladium-catalyzed coupling processes, while the hydrochloride salt enhances bench stability and simplifies purification. Its functional group tolerance supports integration into multi-step synthetic sequences for medicinal chemistry applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   0.0961
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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