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Structure of 221295-04-1
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5-Bromopyrazine-2-carbonitrile features a pyrazine core functionalized with bromine at the 5-position and a nitrile group at the 2-position, enabling facile cross-coupling and diversification. This electron-deficient heteroaromatic scaffold integrates readily into pharmaceutical intermediates and advanced materials, offering high reactivity under standard conditions with minimal handling complexity.
5-Bromopyrazine-2-carbonitrile serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its compatible bromine and nitrile functionalities. The molecule exhibits good bench stability and facilitates the construction of substituted pyrazine scaffolds commonly found in kinase inhibitors and agrochemicals. Its dual reactive handles allow for sequential functionalization, supporting efficient access to complex heterocyclic architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: