N-Methyl-L-valine

CAS No. 2480-23-1
Cat. No. CS-0010219
Purity≥98%
MDL No.MFCD00037754

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 2480-23-1

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Description

N-Methyl-L-valine features a methylated amine group that enhances metabolic stability and membrane permeability. This non-proteinogenic amino acid integrates readily into peptide sequences, offering improved pharmacokinetic properties in bioactive molecule design. The branched isopropyl side chain provides steric bulk, enabling selective interactions in target binding environments.

Application

N-Methyl-L-valine serves as a valuable building block in peptide synthesis, offering enhanced metabolic stability and improved membrane permeability compared to its parent amino acid. Its tertiary amine functionality facilitates efficient coupling reactions and provides favorable steric and electronic properties for incorporation into bioactive peptides. The methylated nitrogen enhances resistance to enzymatic degradation, making it particularly useful in the design of peptidomimetics and drug candidates requiring prolonged half-life.

General Information

CAS No. 2480-23-1
Cat. No. CS-0010219
Purity ≥98%
MDL No. MFCD00037754
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₁₃NO₂
Molecular Weight 131.17
Synonym(s) None
SMILES CC(C)[C@H](NC)C(O)=O

Computational Chemistry Data

TPSA 49.33
LogP 0.315
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 3

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Valine and derivatives

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids Biologically-modified Amino Acids

Key Words

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N-Methyl-L-valine

CAS No. 2480-23-1

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