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CS-W001157 4
Total: USD 88.00

2-Amino-2,2-diphenylacetic acid

  • CAS No. 3060-50-2

  • Cat. No. CS-0060495
  • Molecule weight227.26
  • Purity≥95%
  • MDL No.MFCD00008048

*For research and further manufacturing use only, not for direct human use.

2-Amino-2,2-diphenylacetic acid|CS-0060495

Structure of 3060-50-2

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General Information

  • CAS No. 3060-50-2
  • Cat. No. CS-0060495
  • Purity ≥95%
  • MDL No. MFCD00008048
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₃NO₂
  • Molecular Weight 227.26
  • Synonym(s) 2,2-Diphenylglycine
  • SMILES O=C(O)C(C1=CC=CC=C1)(N)C2=CC=CC=C2

Description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.Aceclofenac impurity H EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Application

2-Amino-2,2-diphenylacetic acid serves as a stable, bench-ready building block for the synthesis of chiral α-amino acids and pharmaceutical intermediates. Its diphenyl substitution provides enhanced steric and electronic stability, facilitating selective functionalization at the amino group. The compound functions effectively in standard peptide coupling protocols and enables access to sterically hindered amino acid scaffolds relevant to medicinal chemistry.

Synthesis

  • Route1

    References

    • Skelly, Patricia D.; Ray, Warren J.; Timberlake, Jack W. Journal of Organic Chemistry, 1985 , vol. 50, # 2 p. 267 - 268
  • Route2
    • null|null
      76-93-7
    • ~%
    • In-stock
      2-Amino-2,2-diphenylacetic acid|CS-0060495
      3060-50-2

    References

    • Journal of the American Chemical Society, , vol. 76, p. 1840,1842
  • Route3
    • null|null
      74255-73-5
    • ~23%
    • In-stock
      Triphenylphosphine oxide|CS-Z0018
      791-28-6
    • In-stock
      2-Amino-2,2-diphenylacetic acid|CS-0060495
      3060-50-2

    References

    • J. Gen. Chem. USSR (Engl. Transl.), , vol. 50, # 1 p. 52 - 55,42 - 45

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   1.9735
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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