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CS-W001157 4
Total: USD 88.00

5,6,7,8-Tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine

  • CAS No. 345311-09-3

  • Cat. No. CS-0050470
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5,6,7,8-Tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine|CS-0050470

Structure of 345311-09-3

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General Information

  • CAS No. 345311-09-3
  • Cat. No. CS-0050470
  • Purity ≥97%
  • MDL No. None
  • Storage -20°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₈N₄
  • Molecular Weight 124.14
  • Synonym(s) 1,2,4-Triazolo[4,3-a]pyrazine,5,6,7,8-tetrahydro
  • SMILES C1CN2C=NN=C2CN1

Description

This heterocyclic scaffold features a fully saturated triazolopyrazine core, offering enhanced stability and favorable solubility for medicinal chemistry applications. The saturated ring system supports diverse functionalization at key positions, enabling integration into bioactive molecules with improved metabolic profiles.

Application

5,6,7,8-Tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine serves as a versatile heterocyclic scaffold in medicinal chemistry, enabling the construction of biologically active compounds through established functionalization pathways. Its saturated core offers enhanced metabolic stability and favorable solubility profiles, while maintaining compatibility with common coupling reactions and protecting group strategies. This robust framework facilitates efficient synthesis of complex molecular architectures relevant to drug discovery programs.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   42.74
  • LogP   -0.6187
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   0

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