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Structure of 349-55-3
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3-Methoxy-5-(trifluoromethyl)aniline features a trifluoromethyl group that imparts enhanced electron-withdrawing character and metabolic stability, while the methoxy substituent provides a polar handle for further functionalization. This combination enables efficient integration into bioactive scaffolds and advanced materials.
3-Methoxy-5-(trifluoromethyl)aniline serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated aromatic scaffolds via standard coupling reactions. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the methoxy substituent offers predictable regioselectivity in electrophilic substitution. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for multi-step synthetic sequences in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: