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Structure of 393-15-7
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4-Methoxy-3-(trifluoromethyl)aniline features a trifluoromethyl group that imparts enhanced electron-withdrawing character and metabolic stability, while the methoxy substituent provides moderate electron-donating effects. This balance enables precise tuning of electronic properties in pharmaceutical intermediates and functional materials. The compound exhibits excellent bench stability and compatibility with diverse synthetic transformations under standard conditions.
4-Methoxy-3-(trifluoromethyl)aniline serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its electron-donating methoxy group and strongly electron-withdrawing trifluoromethyl moiety create a unique electronic profile that enhances reactivity in coupling reactions and facilitates functionalization at multiple sites. The compound exhibits good bench stability, ease of purification, and compatibility with standard synthetic protocols, making it valuable for process-scale applications and targeted scaffold development.
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302+H312-H315-H319-H331-H335
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: