L-Valyl-L-phenylalanine

CAS No. 3918-92-1
Cat. No. CS-7910
Purity≥98%
MDL No.MFCD00020423

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 3918-92-1

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Description

L-Valyl-L-phenylalanine is a dipeptide featuring a valine residue linked via a peptide bond to phenylalanine, offering enhanced stability and solubility in aqueous systems. This combination enables efficient integration into synthetic peptide workflows, particularly in the development of bioactive sequences requiring hydrophobic character and metabolic resistance.

Application

L-Valyl-L-phenylalanine serves as a stable dipeptide building block for peptide synthesis, offering reliable coupling efficiency and orthogonal protection compatibility. Its well-defined stereochemistry ensures fidelity in sequence assembly, while the aliphatic valine side chain provides favorable solubility and reduced aggregation during solid-phase synthesis. This dipeptide functions effectively in the construction of bioactive peptides and pharmaceutical intermediates.

General Information

CAS No. 3918-92-1
Cat. No. CS-7910
Purity ≥98%
MDL No. MFCD00020423
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₄H₂₀N₂O₃
Molecular Weight 264.32
Synonym(s) Valylphenylalanine; H-VAL-PHE-OH
SMILES O=C([C@@H](N)C(C)C)N[C@H](C(O)=O)CC1=CC=CC=C1

Computational Chemistry Data

TPSA 92.42
LogP 0.7818
H_Acceptors 3
H_Donors 3
Rotatable_Bonds 6

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Bioactive Molecules Natural Products

Building Blocks Functional Group Amine

Building Blocks Functional Group Carboxylic Acid

Building Blocks Functional Group Amide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Phenylalanine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

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L-Valyl-L-phenylalanine

CAS No. 3918-92-1

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