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(R)-3-Amino-1-methylpyrrolidin-2-one hydrochloride

  • CAS No. 549531-11-5

  • Cat. No. CS-0435485
  • Molecule weight150.61
  • Purity≥97%
  • MDL No.MFCD30803153

*For research and further manufacturing use only, not for direct human use.

(R)-3-Amino-1-methylpyrrolidin-2-one hydrochloride|CS-0435485

Structure of 549531-11-5

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General Information

  • CAS No. 549531-11-5
  • Cat. No. CS-0435485
  • Purity ≥97%
  • MDL No. MFCD30803153
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₁ClN₂O
  • Molecular Weight 150.61
  • Synonym(s) None
  • SMILES O=C1[C@@H](CCN1C)N.Cl

Description

(R)-3-Amino-1-methylpyrrolidin-2-one hydrochloride is a bench-stable, moisture-tolerant chiral building block featuring a stereodefined amino-pyrrolidone core. This configuration enables direct incorporation into bioactive molecule scaffolds, where its polar amine and carbonyl groups facilitate hydrogen bonding and solubility in aqueous-organic mixtures.

Application

(R)-3-Amino-1-methylpyrrolidin-2-one hydrochloride serves as a versatile chiral building block in medicinal chemistry, enabling efficient access to bioactive heterocycles. Its amine and carbonyl functionalities support diverse transformations, including alkylation, acylation, and coupling reactions, with enhanced solubility and stability under standard synthetic conditions. The compound’s defined stereochemistry facilitates precise control in target-oriented synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   46.33
  • LogP   -0.4024
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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