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Structure of 57339-57-8
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6-Bromoquinolin-8-amine features a quinoline scaffold bearing bromine at the 6-position and an amino group at the 8-position, enabling direct functionalization in cross-coupling reactions. This electron-deficient heterocycle serves as a key building block for pharmaceutical intermediates and advanced materials, offering high reactivity under palladium catalysis.
6-Bromoquinolin-8-amine serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C8 position via palladium-catalyzed cross-coupling reactions. Its bromine atom exhibits high reactivity in Suzuki, Stille, and Negishi couplings, while the aniline functionality offers orthogonal handling for further derivatization. The molecule demonstrates excellent bench stability and facilitates efficient purification, making it well-suited for modular synthesis of quinoline-based scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: