1-Cyclopropylpiperidin-4-amine

CAS No. 62813-02-9
Cat. No. CS-0100626
Purity≥98%
MDL No.None

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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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1-Cyclopropylpiperidin-4-amine|CS-0100626

Structure of 62813-02-9

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Description

1-Cyclopropylpiperidin-4-amine features a cyclopropyl group attached to a piperidine ring, delivering enhanced metabolic stability and improved membrane permeability. This scaffold integrates readily into bioactive molecules, serving as a key building block in medicinal chemistry for CNS-targeted therapeutics and kinase inhibitors.

Application

1-Cyclopropylpiperidin-4-amine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles and pharmaceutical scaffolds. Its tertiary amine functionality offers favorable solubility and metabolic stability, while the cyclopropyl group enhances conformational rigidity and lipophilic interactions. The compound exhibits excellent bench stability and compatibility with standard coupling reactions, facilitating efficient synthesis of targeted compounds through straightforward functionalization.

General Information

CAS No. 62813-02-9
Cat. No. CS-0100626
Purity ≥98%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₆N₂
Molecular Weight 140.23
Synonym(s) 4-Amino-1-cyclopropylpiperidine, (4-Aminopiperidin-1-yl)cyclopropane
SMILES NC1CCN(C2CC2)CC1

Computational Chemistry Data

TPSA 29.26
LogP 0.5719
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

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1-Cyclopropylpiperidin-4-amine

CAS No. 62813-02-9

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