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Structure of 6418-38-8
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2,3-Difluorophenol was used in the synthesis of material-poly{methyl[3-(2-hydroxy-3,4-difluoro)phenyl]propyl siloxane} (PMDFPS) sensitive to toxic organophosphate.
2,3-Difluorophenol serves as a valuable building block in medicinal chemistry and agrochemical synthesis, offering enhanced metabolic stability and modulated lipophilicity due to its ortho-fluorine substitution pattern. The phenolic hydroxyl group enables direct functionalization or derivatization, while the difluoro substitution facilitates regioselective electrophilic aromatic substitution and provides favorable electronic effects for coupling reactions. Its bench-stable nature and compatibility with standard synthetic protocols make it a practical choice for constructing bioactive heterocyclic scaffolds and fluorinated aromatic intermediates.
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GHS No : GHS02,GHS07
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Signal Word : Danger
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UN#: 1325
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Class : 4.1
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Packing Group : Ⅱ
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Hazard Statements : H226-H302-H315-H319-H335-H411
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P273-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P391-P405-P501
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