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CS-W001157 4
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5-Iodopent-1-ene,98% (stabilized with MEHQ)

  • CAS No. 7766-48-5

  • Cat. No. CS-0135974
  • Molecule weight196.03
  • Purity97% (stabilized with MEHQ)
  • MDL No.MFCD19688471

*For research and further manufacturing use only, not for direct human use.

5-Iodopent-1-ene,98% (stabilized with MEHQ)|CS-0135974

Structure of 7766-48-5

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General Information

  • CAS No. 7766-48-5
  • Cat. No. CS-0135974
  • Purity 97% (stabilized with MEHQ)
  • MDL No. MFCD19688471
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₉I
  • Molecular Weight 196.03
  • Synonym(s) 5-Iodo-1-pentene
  • SMILES C=CCCCI

Description

5-Iodopent-1-ene, 98% (stabilized with MEHQ) features a reactive terminal alkene paired with a pendant iodide, enabling efficient cross-coupling transformations. The stabilizing MEHQ prevents polymerization during storage and handling. This bench-stable reagent integrates readily into synthetic sequences requiring halogenated olefins.

Application

5-Iodopent-1-ene, 98% (stabilized with MEHQ) serves as a versatile vinyl iodide building block for palladium-catalyzed cross-coupling reactions. Its terminal alkene functionality enables efficient Heck, Suzuki-Miyaura, and Sonogashira couplings, while the stabilized form ensures bench longevity and reliable performance in multi-step synthesis.

Synthesis

  • Route1
    • null|null
      1119-51-3
    • ~97%
    • In-stock
      5-Iodopent-1-ene,98% (stabilized with MEHQ)|CS-0135974
      7766-48-5

    References

    • Ingenito, Raffaele; Burton, Charlotte; Langella, Annunziata; Chen, Xun; Zytko, Karolina; Pessi, Antonello; Wang, Jun; Bianchi, Elisabetta Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 1 p. 236 - 239
  • Route2

    References

    • Lin, Yuya A.; Chalker, Justin M.; Floyd, Nicola; Bernardes, Goncalo J. L.; Davis, Benjamin G. Journal of the American Chemical Society, 2008 , vol. 130, # 30 p. 9642 - 9643
  • Route3
    • Pent-4-en-1-yl 4-methylbenzenesulfonate|CS-1634855
      19300-54-0
    • ~%
    • In-stock
      5-Iodopent-1-ene,98% (stabilized with MEHQ)|CS-0135974
      7766-48-5

    References

    • Garelli; Vierling Journal of Organic Chemistry, 1992 , vol. 57, # 11 p. 3046 - 3051

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H225-H302-H312-H315-H319-H332-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   2.3876
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   3

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