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Structure of 85822-16-8
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4-Formylbenzenesulfonyl chloride features a sulfonyl chloride group paired with an aldehyde functionality, enabling dual reactivity for conjugate addition and acylation. This bifunctional electrophile facilitates the synthesis of complex aromatic scaffolds under mild conditions.
4-Formylbenzenesulfonyl chloride serves as a versatile bifunctional building block for the synthesis of sulfonamide-containing scaffolds and heterocycles. Its formyl group enables direct incorporation into Ugi-type multicomponent reactions, while the sulfonyl chloride moiety facilitates rapid coupling with amines or alcohols under mild conditions. The reagent exhibits good bench stability and is compatible with common protecting groups, enabling efficient access to complex molecular architectures in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: