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Structure of 1788-10-9
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4-Acetylbenzenesulfonyl chloride features a sulfonyl chloride group flanked by an electron-withdrawing acetyl substituent, enabling selective acylation in synthetic transformations. This bench-stable reagent integrates efficiently into complex molecule assembly, particularly in pharmaceutical intermediates and functionalized aromatic systems.
4-Acetylbenzenesulfonyl chloride serves as a versatile sulfonylating agent for the synthesis of sulfonamide derivatives and functionalized aromatic systems. Its acetyl group enables subsequent transformations such as Claisen condensations or enolate-mediated functionalizations, while the sulfonyl chloride moiety facilitates efficient coupling with amines under mild conditions. The molecule exhibits good bench stability and is compatible with common protecting groups, making it a practical choice for building complex scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314-H318
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: