(S)-N-Boc-2-aminomethylmorpholine

CAS No. 879403-42-6
Cat. No. CS-M3378
Purity≥97%
MDL No.MFCD11707017

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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(S)-N-Boc-2-aminomethylmorpholine|CS-M3378

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Description

(S)-N-Boc-2-aminomethylmorpholine features a chiral morpholine scaffold with a stable Boc-protected amine, enabling direct incorporation into peptide and small-molecule syntheses. This bench-stable derivative facilitates efficient coupling reactions under standard conditions, offering precise stereochemical control in complex molecular architectures.

Application

(S)-N-Boc-2-aminomethylmorpholine serves as a versatile chiral building block for the synthesis of bioactive molecules, enabling efficient access to morpholine-containing scaffolds. Its Boc-protected amine and pendant morpholine ring provide orthogonal reactivity, facilitating selective functionalization in multi-step sequences. The compound exhibits excellent bench stability, simplifies purification, and functions reliably in standard coupling and reduction protocols common in medicinal chemistry workflows.

General Information

CAS No. 879403-42-6
Cat. No. CS-M3378
Purity ≥97%
MDL No. MFCD11707017
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₂₀N₂O₃
Molecular Weight 216.28
Synonym(s) tert-Butyl-(2S)-2-(aminomethyl)morpholin-4-carboxylat
SMILES NC[C@@H]1OCCN(C(OC(C)(C)C)=O)C1

Computational Chemistry Data

TPSA 64.79
LogP 0.581
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Amine

Building Blocks Skeleton Aliphatic heterocycle compounds Morpholine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(S)-N-Boc-2-aminomethylmorpholine

CAS No. 879403-42-6

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