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Structure of 885520-35-4
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4-Bromo-6-fluoro-1H-indazole is a heterocyclic building block featuring complementary halogen substituents at the 4- and 6-positions, enabling sequential cross-coupling reactions. The electron-deficient indazole core facilitates transition-metal-mediated functionalization, while the fluorine atom enhances metabolic stability and modulates electronic properties in bioactive molecule design.
4-Bromo-6-fluoro-1H-indazole serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its compatible halogen substituents. The fluorine and bromine groups offer orthogonal reactivity for sequential functionalization, while the indazole core provides a rigid, bioactive scaffold. Its bench stability and ease of purification support efficient synthesis workflows in API development and heterocyclic library construction.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: