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CS-W001157 4
Total: USD 88.00

5-Azacytosine

  • CAS No. 931-86-2

  • Cat. No. CS-0008471
  • Molecule weight112.09
  • Purity≥97%
  • MDL No.MFCD00006033

*For research and further manufacturing use only, not for direct human use.

5-Azacytosine|CS-0008471

Structure of 931-86-2

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General Information

  • CAS No. 931-86-2
  • Cat. No. CS-0008471
  • Purity ≥97%
  • MDL No. MFCD00006033
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₄N₄O
  • Molecular Weight 112.09
  • Synonym(s) None
  • SMILES O=C1NC(N)=NC=N1

Description

Our SAFC portfolio of high-quality products for biopharmaceutical processing withstands strict quality control procedures and is produced according to MQ-500 requirements as defined by the M-Clarity program.M-Clarity ProgramAs part of our EMPROVE Program, our raw materials are offered with EMPROVE Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

Application

5-Azacytosine serves as a cornerstone nucleobase analog in medicinal chemistry, enabling site-specific DNA methylation studies and epigenetic research. Its enhanced reactivity toward methyltransferases facilitates targeted inhibition, while the pyridine-like nitrogen improves metabolic stability. The compound functions reliably in oligonucleotide synthesis and acts as a key building block for antiviral and anticancer prodrugs.

Synthesis

  • Route1
    • null|null
      10043-39-7
    • In-stock
      DMF-DMA|CS-0016065
      4637-24-5
    • ~87%
    • In-stock
      5-Azacytosine|CS-0008471
      931-86-2

    References

    • Vujjini, Satish Kumar; Varanasi, Ganesh; Arevelli, Srinivas; Kandala, Sreenatha Charyulu; Tirumalaraju, Satyanarayana Raju; Bandichhor, Rakeshwar; Kagga, Mukkanti; Cherukupally, Praveen Organic Process Research and Development, 2013 , vol. 17, # 2 p. 303 - 306
  • Route2
    • In-stock
      Decitabine|CS-0372
      2353-33-5
    • ~%
    • In-stock
      5-Azacytosine|CS-0008471
      931-86-2
    • null|null
      452-51-7

    References

    • US2006/205685 A1, ; Page/Page column 4; sheet 3 ;
  • Route3
    • Guanylurea|CS-0641028
      141-83-3
    • null|null
      122-51-0
    • ~%
    • In-stock
      5-Azacytosine|CS-0008471
      931-86-2

    References

    • WO2010/17374 A1, ; Page/Page column 18 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   84.66
  • LogP   -1.2529
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   0

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