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Structure of 433-94-3
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2-Chloro-6-(trifluoromethyl)aniline features a trifluoromethyl group that imparts strong electron-withdrawing character, enhancing reactivity in coupling processes. The ortho-chloro substituent enables selective functionalization, while the amine handle facilitates incorporation into pharmaceutical intermediates and advanced materials.
2-Chloro-6-(trifluoromethyl)aniline serves as a versatile building block in medicinal chemistry, enabling direct incorporation of both chlorine and trifluoromethyl groups into heterocyclic scaffolds. Its stability under standard reaction conditions facilitates palladium-catalyzed couplings, nucleophilic substitutions, and electrophilic aromatic substitutions. The molecule’s defined regiochemistry supports predictable functionalization in API synthesis and offers favorable handling characteristics for bench-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H227-H302+H312+H332-H315-H319
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Precautionary Statements : P210-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P403-P501
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Lot numbers can be found on the outside label of a product: