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Structure of 39885-50-2
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2-Chloro-4-(trifluoromethyl)aniline features a trifluoromethyl group that imparts enhanced electron-withdrawing character and metabolic stability, while the ortho-chloro substituent enables directed functionalization. This combination delivers improved solubility in organic media and robust performance under standard bench conditions, making it a reliable intermediate for pharmaceutical and agrochemical synthesis.
2-Chloro-4-(trifluoromethyl)aniline serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of heterocyclic scaffolds via palladium-catalyzed coupling reactions. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the chloro substituent provides a reliable handle for further functionalization through cross-coupling or nucleophilic substitution. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for scalable synthetic workflows.
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GHS Pictogram :
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GHS No : GHS06,GHS09
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301+H311-H315-H319-H332-H335-H410
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Precautionary Statements : P261-P264-P270-P271-P273-P280-P302+P352-P304+P340-P330-P361+P364-P362+P364-P391-P405-P501
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Lot numbers can be found on the outside label of a product: