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Structure of 3167-50-8
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2-Aminopyrimidine-5-carboxylic acid features a dual functional group architecture combining a nucleophilic amine and an electron-deficient carboxylic acid within a pyrimidine scaffold. This arrangement enables direct integration into heterocyclic scaffolds via amidation or coupling reactions, offering high reactivity under standard conditions. The molecule exhibits enhanced solubility in polar solvents and stability under ambient handling.
2-Aminopyrimidine-5-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of heterocyclic scaffolds through standard coupling and cyclization protocols. Its dual functional groups—amine and carboxylic acid—facilitate diverse derivatization, including amide formation and metal-catalyzed cross-couplings. The compound exhibits good bench stability and is readily purified by recrystallization, supporting its use in scalable API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: