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CS-W001157 4
Total: USD 88.00

1-(5-Hydroxypyridin-2-yl)ethanone

  • CAS No. 67310-56-9

  • Cat. No. CS-W021245
  • Purity≥98%
  • MDL No.MFCD10697710
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-(5-Hydroxypyridin-2-yl)ethanone|CS-W021245

Structure of 67310-56-9

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Description

1-(5-Hydroxypyridin-2-yl)ethanone features a pyridine ring bearing both hydroxyl and ketone functionalities at adjacent positions, enabling dual coordination sites for metal chelation. This structural motif supports integration into ligand frameworks for transition-metal catalysis and offers enhanced solubility in polar solvents compared to analogous non-hydroxylated analogs.

Application

1-(5-Hydroxypyridin-2-yl)ethanone serves as a versatile building block for heterocyclic synthesis, enabling efficient access to pyridine-based scaffolds through standard functional group transformations. Its hydroxyl and ketone functionalities offer orthogonal reactivity, facilitating coupling reactions, derivatization, and protection strategies. The compound exhibits good bench stability and is readily purified by recrystallization or chromatography, making it well-suited for medicinal chemistry and process development workflows.

General Information

  • CAS No. 67310-56-9
  • Cat. No. CS-W021245
  • Purity ≥98%
  • MDL No. MFCD10697710
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇NO₂
  • Molecular Weight 137.14
  • Synonym(s) Ethanone, 1-(5-hydroxy-2-pyridinyl)- (9CI)
  • SMILES CC(C1=NC=C(O)C=C1)=O

Computational Chemistry Data

  • TPSA   50.19
  • LogP   0.9898
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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