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Structure of 67310-56-9
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1-(5-Hydroxypyridin-2-yl)ethanone features a pyridine ring bearing both hydroxyl and ketone functionalities at adjacent positions, enabling dual coordination sites for metal chelation. This structural motif supports integration into ligand frameworks for transition-metal catalysis and offers enhanced solubility in polar solvents compared to analogous non-hydroxylated analogs.
1-(5-Hydroxypyridin-2-yl)ethanone serves as a versatile building block for heterocyclic synthesis, enabling efficient access to pyridine-based scaffolds through standard functional group transformations. Its hydroxyl and ketone functionalities offer orthogonal reactivity, facilitating coupling reactions, derivatization, and protection strategies. The compound exhibits good bench stability and is readily purified by recrystallization or chromatography, making it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: