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Structure of 1000343-69-0
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6-Bromo-5-methyl-1H-indazole is a heterocyclic scaffold featuring a bromine substituent at the 6-position and a methyl group at the 5-position, enabling selective functionalization in medicinal chemistry. This electron-deficient indazole core integrates readily into kinase inhibitors and bioactive molecules, offering enhanced metabolic stability and targeted binding affinity.
6-Bromo-5-methyl-1H-indazole serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions for the construction of biaryl and heteroaryl scaffolds. The bromine atom facilitates efficient C–Br bond functionalization under standard conditions, while the methyl group enhances metabolic stability and modulates electronic properties. Its bench-stable nature and compatibility with diverse reaction conditions make it ideal for modular synthesis of targeted API candidates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: