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Structure of 885223-72-3
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5-Bromo-6-methyl-1H-indazole is a heterocyclic scaffold featuring a bromine atom at the 5-position and a methyl group at the 6-position, enabling selective functionalization in medicinal chemistry. This electron-deficient indazole integrates readily into bioactive molecules, offering enhanced metabolic stability and favorable binding interactions in target-directed synthesis.
5-Bromo-6-methyl-1H-indazole serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-established bromine functionality. The methyl group at the 6-position enhances metabolic stability and modulates electronic properties, while the indazole core provides a robust hydrogen-bonding scaffold for target engagement. Its bench-stable crystalline form facilitates handling and purification, making it ideal for iterative synthesis of kinase inhibitors and other bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: