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Structure of 1001756-21-3
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4-Amino-6-chloronicotinaldehyde features a strategically positioned aldehyde group flanked by electron-donating amino and electron-withdrawing chloro substituents, enabling selective coupling reactions in heterocyclic synthesis. This bench-stable scaffold integrates readily into bioactive molecule architectures requiring polar functionality and tailored electronic properties.
4-Amino-6-chloronicotinaldehyde serves as a versatile building block in medicinal chemistry, enabling the synthesis of heterocyclic scaffolds via condensation and cyclization reactions. Its dual functional groups—aldehyde and amino—facilitate efficient derivatization under mild conditions, while the chlorine substituent supports further cross-coupling transformations. The compound exhibits good bench stability and is amenable to purification by chromatography or recrystallization, making it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: