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Structure of 1005206-25-6
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This boronate ester features a trifluoromethylthio-substituted phenyl ring, enhancing electronic modulation and stability. The tetramethyl-substituted dioxaborolane core provides excellent shelf life and reactivity in Suzuki-Miyaura cross-coupling reactions under standard conditions.
4,4,5,5-Tetramethyl-2-(4-((trifluoromethyl)thio)phenyl)-1,3,2-dioxaborolane serves as a stable, bench-ready boronate building block for palladium-catalyzed cross-coupling reactions. Its trifluoromethylthio-substituted aryl group enables efficient Suzuki-Miyaura coupling with diverse electrophiles, offering enhanced metabolic stability and lipophilicity in medicinal chemistry applications. The sterically protected dioxaborolane core ensures high chemical stability, minimal protodeboronation, and straightforward purification by flash chromatography or crystallization.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H413
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Precautionary Statements : P264-P270-P273-P330
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Lot numbers can be found on the outside label of a product: