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CS-W001157 4
Total: USD 88.00

2,6-Diethylphenol

  • CAS No. 1006-59-3

  • Cat. No. CS-W006844
  • Purity≥98%
  • MDL No.MFCD01707589

*For research and further manufacturing use only, not for direct human use.

2,6-Diethylphenol|CS-W006844

Structure of 1006-59-3

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General Information

  • CAS No. 1006-59-3
  • Cat. No. CS-W006844
  • Purity ≥98%
  • MDL No. MFCD01707589
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₄O
  • Molecular Weight 150.22
  • Synonym(s) None
  • SMILES OC1=C(CC)C=CC=C1CC

Description

2,6-Diethylphenol features a phenolic hydroxyl group flanked by two ethyl substituents at the 2 and 6 positions, creating a sterically hindered, electron-rich aromatic system. This configuration enhances stability and modulates reactivity, making it valuable for selective derivatization in synthetic organic chemistry and as a building block in functional materials.

Application

2,6-Diethylphenol serves as a valuable building block in the synthesis of functionalized aromatic systems, offering enhanced steric and electronic modulation compared to unsubstituted phenols. Its ortho-alkyl substituents provide improved bench stability and reduce unwanted side reactions during electrophilic substitution or coupling processes. The phenolic hydroxyl group enables straightforward derivatization—such as etherification, esterification, or metalation—facilitating access to complex scaffolds used in agrochemicals and specialty materials.

Synthesis

  • Route1

    References

    • Ieda, Naoya; Nakagawa, Hidehiko; Horinouchi, Taeko; Peng, Tao; Yang, Dan; Tsumoto, Hiroki; Suzuki, Takayoshi; Fukuhara, Kiyoshi; Miyata, Naoki Chemical Communications, 2011 , vol. 47, # 22 p. 6449 - 6451
  • Route2
    • In-stock
      2,6-Diethylaniline|CS-W018171
      579-66-8
    • null|null
      7664-93-9
    • ~%
    • In-stock
      2,6-Diethylphenol|CS-W006844
      1006-59-3

    References

    • US2003/119813 A1, ;
  • Route3
    • null|null
      17326-35-1
    • ~65%
    • In-stock
      2,6-Diethylphenol|CS-W006844
      1006-59-3

    References

    • Burroughs Wellcome Co. Patent: US4116958 A1, 1978 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P264-P270-P280-P301+P310-P305+P351+P338-P330-P337+P313-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.517
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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