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Structure of 1008119-07-0
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This boronic acid ester features a difluorinated aryl core paired with a tetramethyl-1,3,2-dioxaborolane handle, enabling reliable Suzuki-Miyaura cross-coupling under standard conditions. The carboxylic acid group provides a polar anchor for downstream conjugation and enhances solubility in aqueous-organic mixtures.
2,6-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The difluorophenyl moiety enhances metabolic stability and modulates electronic properties, while the pinacol boronate group ensures excellent bench stability and compatibility with a broad range of reaction conditions. This reagent facilitates efficient construction of substituted biaryl scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: