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CS-W001157 4
Total: USD 88.00

2-(Pyridin-4-yl)morpholine

  • CAS No. 1018656-57-9

  • Cat. No. CS-W021459
  • Molecule weight164.20
  • Purity≥98%
  • MDL No.MFCD10035256

*For research and further manufacturing use only, not for direct human use.

2-(Pyridin-4-yl)morpholine|CS-W021459

Structure of 1018656-57-9

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General Information

  • CAS No. 1018656-57-9
  • Cat. No. CS-W021459
  • Purity ≥98%
  • MDL No. MFCD10035256
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂N₂O
  • Molecular Weight 164.20
  • Synonym(s) None
  • SMILES C1(C2=CC=NC=C2)CNCCO1

Description

2-(Pyridin-4-yl)morpholine features a pyridyl group conjugated to a morpholine ring, delivering enhanced solubility and basicity. This combination enables effective hydrogen bonding and π-stacking interactions in medicinal chemistry applications. The molecule exhibits bench-stable handling characteristics and integrates readily into diverse synthetic scaffolds.

Application

2-(Pyridin-4-yl)morpholine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to bioactive scaffolds through standard coupling and functionalization reactions. Its pyridine moiety provides enhanced solubility and hydrogen-bonding capacity, while the morpholine ring offers favorable metabolic stability and moderate basicity. The compound exhibits good bench stability, facile purification, and compatibility with diverse reaction conditions, making it well-suited for iterative synthesis workflows and lead optimization campaigns.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   34.15
  • LogP   0.7425
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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