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Structure of 321724-19-0
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Pyrimidine-5-boronic acid pinacol ester delivers a stable, bench-ready boronate handle for cross-coupling reactions. This moisture-tolerant reagent integrates seamlessly into Suzuki-Miyaura protocols, enabling efficient C–C bond formation at the pyrimidine 5-position. The pinacol ester moiety enhances solubility and handling while maintaining high reactivity under standard conditions.
Pyrimidine-5-boronic acid pinacol ester serves as a stable, bench-ready building block for Suzuki-Miyaura cross-coupling reactions. Its robust boronate ester functionality enables efficient C–C bond formation with aryl and vinyl halides under mild conditions, facilitating the construction of complex pyrimidine-containing scaffolds. The pinacol protection enhances solubility and simplifies purification, making it ideal for medicinal chemistry campaigns and process-scale synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: