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Structure of 1025719-23-6
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1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)-1H-pyrazole features a boronate ester group paired with a trifluoromethyl-substituted pyrazole core, enabling efficient Suzuki-Miyaura coupling. This bench-stable reagent integrates readily into C–C bond formation workflows, delivering high functional group tolerance and predictable regiochemistry under standard conditions.
1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)-1H-pyrazole serves as a robust boronate building block in Suzuki-Miyaura cross-coupling reactions. The tetramethylboronate moiety enables efficient coupling with aryl and vinyl halides under mild conditions, while the trifluoromethyl group imparts enhanced metabolic stability and lipophilicity. Bench-stable and readily purified by flash chromatography, it functions reliably in the synthesis of complex heterocyclic scaffolds and drug-like molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: