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Structure of 102624-96-4
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Azetidine-3-carboxylic acid hydrochloride is a conformationally constrained, nitrogen-rich heterocycle featuring a strained four-membered ring that imparts rigidity to peptide backbones. This scaffold integrates readily into bioactive molecules, enhancing metabolic stability and modulating target affinity through defined spatial orientation. The hydrochloride salt improves solubility and handling under standard bench conditions.
Azetidine-3-carboxylic acid hydrochloride serves as a conformationally constrained proline analog, enabling the stabilization of bioactive peptide conformations. Its four-membered ring structure facilitates backbone rigidity in peptidomimetics, while the carboxylic acid group supports direct coupling reactions. The hydrochloride salt enhances bench stability and solubility, simplifying handling and purification in solid-phase and solution-phase synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: