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Structure of 102638-45-9
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tert-Butyl 3-(aminomethyl)benzoate features a benzoyl scaffold bearing both a tert-butyl ester and a primary amine at the meta position, enabling direct functionalization. This dual functionality supports efficient coupling reactions and facilitates downstream derivatization in medicinal chemistry. The compound exhibits excellent stability under standard bench conditions and is compatible with common protecting group strategies.
tert-Butyl 3-(aminomethyl)benzoate serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its benzoate scaffold enables facile functionalization at the para-position, while the pendant primary amine facilitates conjugation reactions, reductive amination, or incorporation into peptide-like frameworks. The tert-butyl ester group provides bench stability and can be selectively removed under mild acidic conditions, offering flexibility in late-stage deprotection during synthetic sequences.
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3259
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H312-H315-H318-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P330-P363-P405-P501
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Lot numbers can be found on the outside label of a product: