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Structure of 1028748-08-4
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This boronate moiety integrates a rigid, electron-rich dihydrobenzofuran scaffold with enhanced stability and moisture tolerance. The sterically shielded 2,2-dimethyl substitution prevents protodeboronation while maintaining reactivity in Suzuki-Miyaura couplings. Ideal for constructing complex heterocyclic architectures under mild conditions.
(2,2-Dimethyl-2,3-dihydrobenzofuran-5-yl)boronic acid serves as a stable, bench-ready building block for Suzuki-Miyaura cross-coupling reactions. Its rigid, electron-rich dihydrobenzofuran core enhances regioselectivity and functional group tolerance, enabling efficient access to substituted biaryl and heteroaryl scaffolds. The sterically protected boronic acid resists protodeboronation and simplifies purification, making it well-suited for medicinal chemistry and process-scale synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319
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Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: