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Structure of 1033203-48-3
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4-Amino-6-bromopyridin-3-ol features a pyridine core functionalized with amino, bromo, and hydroxyl groups at the 4, 6, and 3 positions, respectively. This tri-functional scaffold enables direct incorporation into heterocyclic architectures. The electron-rich amine pairs effectively with the electron-deficient bromine for cross-coupling transformations. The phenolic hydroxyl enhances solubility and facilitates derivatization. This compound serves as a key building block in medicinal chemistry and materials synthesis.
4-Amino-6-bromopyridin-3-ol serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the pyridine core through palladium-catalyzed cross-coupling reactions. The amino and hydroxyl groups provide orthogonal handles for derivatization, while the bromine facilitates C–C bond formation under standard Suzuki or Negishi conditions. Bench-stable and readily purified by recrystallization, it functions efficiently in the synthesis of bioactive heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: